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Normalized glandular dose (DgN) coefficients from experimental mammographic x-ray spectra

Santos, Tomal, de Barros, Costa

“Polyenergetic x-ray spectrometry proved to be an applicable tool for research in dosimetry in mammography allowing spectral characterization.”

Impact of compressed breast thickness and dose on lesion detectability in digital mammography: FROC study with simulated lesions in real mammograms

Salvagnini, Bosmans, Van Ongeval, Van Steen, Michielsen, Cockmartin, Struelens, Marshall

“These data using clinical images confirm results found in simple QA tests for many mammography systems that detectability falls as breast thickness increases.”

Comparison of a personalized breast dosimetry method with standard dosimetry protocols

Salomon, Homolka, Semturs, Figl, Gruber, Hummel

“In this study we compared three diferent methods of estimating glandularities according to Wu, Dance and Volpara with respect to resulting AGDs .. As the Volpara method provides an analysis of the individual breast tissue, while the Wu and the Dance methods use look up tables and custom parameter sets, the Volpara method might be more appropriate if individual ADG values are sought.”

MRI versus mammography for breast cancer screening in women with familial risk (FaMRIsc): a multicentre, randomised, controlled trial

Saadatmand, Geuzinge, Rutgers, Mann, van Zuidewijn, Zonderland, Tollenaar, Lobbes, Ausems, van 't Riet, Hooning, Mares-Engelberts, Luiten, Heijnsdijk, Verhoef, Karssemeijer, Oosterwijk, Obdeijn, de Koning, Tilanus-Linthorst

“MRI screening detected cancers at an earlier stage than mammography. The lower number of late-stage cancers identified in incident rounds might reduce the use of adjuvant chemotherapy and decrease breast cancer-related mortality.”

Volumetric breast density and risk of advanced cancers after a negative screening episode: a cohort study

Puliti, Zappa, Rossi, Pierpaoli, Manneschi, Ambrogetti, Ventura, Mantellini

“BD has a strong impact on the risk of advanced cancers after a negative screening episode, the best early surrogate of BC mortality. Therefore, our results suggest that screening effectiveness is quite different among BD categories.”

Determination of personalized mean glandular dose using estimates of the glandular tissue distribution in a clinical setting

Porras-Chaverri, Mora, Vetter, Highnam

“Differences of up to 19% were found between the dose coefficients calculated using the traditional geometry with respect to those calculated using the HLB geometry. These differences are due solely to the individual distributions of glandular tissue. “

Mammographic Breast Density and Urbanization: Interactions with BMI, Environmental, Lifestyle, and Other Patient Factors

Perry, Moss, Dixon, Milner, Mokbel, Lemech, Arkenau, Duffy, Pinker

“Urban residence was significantly associated with an increasing percent of MBD … Our results suggest that the association between urban women and increased MBD can be partially explained by their lower BMI, but for women still working, there appear to be other contributing factors.”

High Volumetric Breast Density Predicts Risk for Breast Cancer in Postmenopausal, but not Premenopausal, Korean Women

Park, Ko, Joo, Park, Jung, Lee, Kwon, Kang, Lee, Lee, Ro

“High volumetric breast density is significantly associated with the risk of breast cancer in postmenopausal women; however, these relationships were not found in premenopausal women.”

Do women with dense breasts have higher radiation dose during screening mammography?

Nguyen, Williams, Patrie, Harvey

“Compressed breast thickness had the greatest effect on average glandular dose. Breast density has a minor impact, while BMI and age have minimal impact on dose.”

Change in mammographic density across birth cohorts of Dutch breast cancer screening participants

Napolitano, Lynge, Lillholm, Vejborg, van Gils, Nielsen, Karssemeijer

“This study based on mammographic density measurements collected over a 13 year period in the Netherlands indicated that density increased over birth cohort in particular for women in their 50s. This could possibly be related to an increasing age of natural menopause, but further longitudinal studies are needed to test this observation.”