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Investigating the feasibility of stratified breast cancer screening using a masking risk predictor

Alonzo-Proulx, Mainprize, Harvey, Yaffe

“The combined VBD/detectability models perform better than BI-RADS and offer a continuum of operating points, suggesting that this model may be effective in guiding a stratified screening environment.”

Background risk of breast cancer influences the association between alcohol consumption and mammographic density

Trinh, Christensen, Brand, Cuzick, Czene, Sjölander, Bälter, Hall

“…increasing alcohol consumption was associated with higher absolute dense volume (cm3) and percent dense volume (%). The association between alcohol consumption and absolute dense volume was most pronounced among women with the highest (≥5%) Tyrer-Cuzick 10-year risk.”

Background risk of breast cancer and the association between physical activity and mammographic density

Trinh, Eriksson, Darabi, Bonn, Brand, Cuzick, Czene, Sjölander, Bälter, Hall

“…higher levels of physical activity were associated with lower absolute dense volume and nondense volume, but seemed to be associated with higher percent dense volume… absolute dense volume seemed to vary according to the risk of developing breast cancer in the next 10 years…Volumetric measures are therefore expected to capture the actual amount of fibroglandular tissue in the breast more precisely.”